Giulia Gemelli
DC6
My passion for analytical chemistry and biological studies is emphasized through the BioTransform project.
I look forward to connect with the other doctoral candidate, to create an open and cooperative working network.
My goal is to identify and characterize bilberry-derived metabolites in humans and elucidate their metabolic pathway using LCMS-based techniques.
DC6: Exploration of metabolism pathways and bioactives’ metabolites from bilberries by using UPLC-HRMS approaches
Supervisor: Priv.-Doz. Dr. Eva Pferschy-Wenzig
Co-Supervisors: Dr. Gints Smits (LIOS); Mrs. Anna Ramata-Stunda (ALT)
Secondments This project is carried out in strong collaboration with the institutions listed below:
- Laboratory of Pharmaceutical Pharmacology, Latvian Institute of Organic Synthesis (LIOS), Riga, Latvia
- Alternative Plants, Riga, Latvia
- Department of Metabolism, Digestion and Reproduction, Imperial College London (ICL), United Kingdom
Project description
The project aims to study bilberries, their metabolic composition, and the biotransformation and metabolic fate of food bioactives, which are vital to confer good health benefits.
From a scientific perspective, via advanced UHPLC-HRMS/MS-based metabolomics of clinical samples (feces, plasma, and urine) the project seeks to identify and characterize metabolites to uncover metabolic pathways associated with beneficial biological effects.
From an industrial perspective, the project aims to identify bioactive metabolites and potential biomarkers that can be linked to health benefits.
Professional background
I completed my bachelor’s degree in chemistry at the University of Milan, and I continued my studies in analytical chemistry through the Erasmus Mundus Joint Master’s Degree in Advanced Spectroscopy in Chemistry. Through my master’s, I had the opportunity to study at the University of Lille in France and at the University of Leipzig in Germany, where I experienced working with metabolomics analyses using LCMS techniques.